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In a very detailed analysis, scientists show that low blood circulating levels of vitamin D do not adequately inhibit the inflammatory cascade necessary to turn off this potentially destructive mechanism. Low levels of inflammation, normally used by the body to fight pathogenic invaders, become a primary cause of heart disease, diabetes, many cancer lines and Alzheimers dementia. Additional evidence reported in the British Journal of Nutrition demonstrates that adequate vitamin D levels reduce critical markers of cardiovascular health and can lead to significant reductions in body fat in overweight and obese people. It is critical to have your vitamin D level checked, and supplement as necessary to lower inflammation levels and risk of heart disease. Dr. Elena Goleva, lead scientist from National Jewish Health, found that prior studies with vitamin D show a clear and positive link between blood levels of the prohormone and a variety of different health outcomes. Dr. Goleva and her team looked for specific mechanisms to explain precisely how vitamin D functions at the cellular level to prevent disease in the human body. Dr. Goleva and her team of researchers noted that vitamin D is a catalyst that initiates a clear chain of cellular events, from the binding of DNA, through a specific signaling pathway, to the reduction of proteins known to trigger inflammation. To test how vitamin D acts on immune and inflammatory pathways, team scientists exposed human white blood cells to varying levels of vitamin D and exposed them to an agent known to promote intense inflammatory responses and advance disease processes.



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