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For example, you cant say one music, two musics, three musics. Names of holidays, countries, companies, languages, etc. are all proper nouns. You dont need to use an article with a proper noun. b. GeographyArticles are not used before countries, states, cities, towns, continents, single lakes, or single mountains. Lake Ontario and Lake Huron are 2 of the Great Lakes. The Great Lakes are a group of lakes on the border between Canada and the US. NOTE: There is an exception to every rule in English. The is part of the names of these countries:the United Statesthe Czech Republicthe PhilippinesNATO ambassadors met to discuss the situation. NATO is the acronym used for the North Atlantic Treaty Organization.
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If you wish to opt out, please close your SlideShare account. Learn more. Topic: Dissertation Proposal E menu systemModule: Research Principles and PracticesDate: Apr 2012Mark: 78%Sheffield Hallam UniversityRetinal degeneration represents a group of blinding diseases that are increasingly impacting the health and well being of Californians. It is estimated that by 2020, over 450,000 Californians will suffer from vision loss or blindness due to the age related macular degeneration AMD, the most common cause of retinal degeneration diseases in the elderly. AMD is a progressive ocular disease of the part of the retina, called the macula, which enables people to read, visualize faces, and drive. The disease initially causes distortion in central vision, and eventually leads to legal blindness. A layer of cells at the back of the eye called the retinal pigment epithelium RPE, provide support, protection, and nutrition to the light sensitive cells of the retina; the photoreceptors which consist of rods and cones . The dysfunction and/or loss of these RPE cells play a critical role in the loss of the PRs and hence the blindness in AMD. Effective treatment could be achieved by proper replacement of damaged RPE and retinal cells with healthy ones. More specifically, the regenerated and restored RPE layer would prevent the irreversible loss of the PRs. However, the lack of a feasible approach to restore the RPE cells has prevented the realization of a potential therapy.